AWS Storage Gateway is a hybrid cloud storage service that allows on-premises applications to seamlessly use cloud storage. Exact Sciences uses it as the foundation for their NGS Data Lake on AWS, benefiting from its flexibility, scalability, and ease of management. This solution helps them manage large amounts of NGS data efficiently while reducing their on-premises infrastructure.

S3 File Gateway enables the transfer of large volumes of NGS data from lab machines to Amazon S3. By deploying multiple Storage Gateway hardware appliances, Exact Sciences can efficiently manage data transfer, which is crucial given their rapidly expanding global lab footprint.

AWS Storage Gateway offers several benefits, including scalable data ingestion that can be rapidly deployed, reduced on-premises infrastructure management and costs, and automated data pipeline management. This leads to accelerated data migration to the cloud and decreased turnaround time for data processing, allowing scientists to access hundreds of terabytes of data more efficiently.